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2012年版WHO乳腺肿瘤分类

2012年版WHO乳腺肿瘤分类

上皮性肿瘤EPITHELIAL TUMOURS

微浸润癌Microinvasive carcinoma


浸润性乳腺癌Invasive breast carcinoma

浸润性癌,非特殊类型 Invasive carcinoma of no specialtype(NST)

多形性癌 Pleomorphic carcinoma

伴破骨巨细胞的癌Carcinoma with osteoclast-like stromal giant cells

伴绒癌特征的癌Carcinoma with choriocarcinomatous features

伴黑色素特征的癌 Carcinoma with melanotic features

浸润性小叶癌Invasive lobular carcinoma

•经典型小叶癌Classic lobular carcinoma

实性型小叶癌Solid lobular carcinoma

腺泡型小叶癌Alveolar lobular carcinoma

多形性小叶癌 Pleomorphic lobular carcinoma

小管小叶癌 Tubulolobular carcinoma

混合性小叶癌 Mixed lobular carcinoma

小管癌Tubular carcinoma

筛状癌 Cribriform carcinoma

黏液癌 Mucinous carcinoma

伴有髓样癌特征的癌 Carcinoma with medullary features

髓样癌 Medullary carcinoma

不典型髓样癌 Atypical medullary carcinoma

具有髓样癌特征的浸润性癌(非特殊类型)

Invasive carcinoma NST with medullary features

伴大汗腺分化的癌 Carcinoma with apocrine differentiation

具有印戒样细胞分化的癌 Carcinoma with signet-ring-cell differentiation

浸润性微乳头状癌 Invasive micropapillary carcinoma

化生性癌,非特殊类型 Metaplastic carcinoma of no special type

低级别腺鳞癌 Low-grade adenosquamous carcinoma

纤维瘤病样化生性癌Fibromatosis-like metaplastic carcinoma

鳞状细胞癌 Squamous cell carcinoma

梭形细胞癌 Spindle cell carcinoma

具有间叶分化的化生性癌 Metaplastic carcinoma with mesenchymal differentiation

软骨分化 Chondroid differentiation

骨分化 Osseous differentiation

其他类型间叶分化 Other type of mesenchymal differentiation

混合性化生性癌 Mixed metaplastic carcinoma

肌上皮癌 Myoepithelial carcinoma

少见类型Rare types

具有神经内分泌特征的癌Carcinoma with neuroendocrine features

神经内分泌肿瘤,分化良好Neuroendocrine tumour ,well-differentiated

神经内分泌癌,低分化 (小细胞癌)

Neuroendocrine carcinoma,poorly differentiated (small cell carcinoma)

伴神经内分泌分化的癌 Carcinoma with neuroendocrine differentiated

分泌型癌 Secretory carcinoma

浸润性乳头状癌 Invasive papillary carcinoma

腺泡细胞癌 Acinic cell carcinoma

黏液表皮样癌 Mucoepidermoid carcinoma

多样性癌(类似涎腺多形性低度恶性腺癌) Plomorphous carcinoma

嗜酸细胞癌 Oncocytic carcinoma

富脂质癌 Lipid-rich carcinoma

富含糖原透明细胞癌 Glycogen-rich clear cell carcinoma

皮脂腺癌 Sebaceous carcinoma

涎腺/皮肤附件型肿瘤Salivary gland/skin adnexal type tumours

圆柱瘤 Cylindroma

透明细胞汗腺瘤 Clear cell hidradenoma

 

上皮-肌上皮肿瘤 Epithelial-myoepithelial tumours

多形性腺瘤 Pleomorphic adenoma

腺肌上皮瘤 Adenomyoepithelioma

腺肌上皮瘤癌变Adenomyoepithelioma with carcinoma

腺样囊性癌 Adenoid cystic carcinoma

 

前驱病变Precursor lesions

导管原位癌Ductal carcinoma in situ

小叶肿瘤 Lobular neoplasia

小叶原位癌 Lobular carcinoma in situ

经典型小叶原位癌Classic lobular carcinoma in situ

多形性小叶原位癌 Pleomorphic lobular carcinoma in situ

非典型小叶增生Atypical lobular heperplasia

 

导管增生性病变Intraductal proliferative lesions

普通型导管增生 Usual ductal hyperplasia

柱状上皮病变,包括平坦型不典型增生

Columnar cell lesions including flat epithelial atypia

非典型导管上皮增生 Atypical ductal hyperplasia

 

乳头状病变Papillary lesions

导管内乳头状瘤 Intraductal papilloma

伴异型增生的导管内乳头状瘤 Intraductal papilloma with atypical hyperplasia

伴导管内原位癌的导管内乳头状瘤 Intraductal papilloma with ductal caicinoma in situ

伴小叶原位癌的导管内乳头状瘤 Intraductal papilloma with lobular carcinoma in situ

导管内乳头状癌Intraductal papillary carcinoma

包裹性乳头状癌 Encapsulated papillary carcinoma

•伴有浸润的包裹性乳头状癌 Encapsulated papillary carcinoma with invasion

实性乳头状癌 Solid papillary carcinoma

原位In situ

浸润 Invasive

 

良性上皮增生Benign epithelial proliferations

硬化性腺病 Sclerosing adenosis

大汗腺腺病 Apocrine adenosis

微腺腺病 Microglandular adenosis

放射状瘢痕/复杂性硬化性病变 Radial scar/complex sclerosing lesion

腺瘤Adenomas

•管状腺瘤Tubular adenoma

•泌乳腺瘤 Lactating adenoma

•大汗腺腺瘤 Apocrine adenoma

•导管腺瘤 Ductal adenoma

 

间叶性肿瘤MESENCHYMAL TUMOURS

结节性筋膜炎Nodular fascietis

肌纤维母细胞瘤Myofibroblastoma

韧带样纤维瘤病Desmoid-type fibromatosis

炎性肌纤维母细胞肿瘤Inflacmatory myofibroblastic tumour

良性血管病变Benign vascular lesions

•血管瘤Haemangioma

•血管瘤病Angiomatosis

•非典型性血管病变Atypical vascular lesions

假血管瘤样增生Pseudoangiomatous stromal hyperplasia

颗粒细胞瘤Granular cell tumour

良性外周神经鞘瘤benign peripheral nerve-sheath tumours

•神经纤维瘤Neurofibroma

•施万细胞瘤Schwannoma

脂肪瘤Lipoma

•血管脂肪瘤Angiolipoma

脂肪肉瘤Liposarcoma

血管肉瘤Angiosarcoma

横纹肌肉瘤Rhabdomyosarcoma

骨肉瘤Osteosarcoma

平滑肌瘤Leiomyoma

平滑肌肉瘤Leiomyosarcoma

 

纤维上皮性肿瘤FIBROEPITHELIAL TUMOURS

纤维腺瘤Fibroadenoma

叶状肿瘤Phyllodes tumour

•良性Benign

•交界性Borderline

•恶性Malignant

•导管周间质肉瘤,低级别Periductal stromal tumour,low grade

错构瘤Hamartoma

 

乳头肿瘤TUMOURS OF THE NIPPLE

乳头腺瘤Nipple adenoma

汗管瘤样腺瘤Syringomatous tumour

乳头派杰氏病Paget disease of the nipple

 

恶性淋巴瘤MALIGNANT LYMPHOMA

弥漫性大B细胞淋巴瘤Diffuse large B-cell lymphoma

伯基特淋巴瘤Burkitt lymphoma

T细胞淋巴瘤T-cell lymphoma

ALK阴性的间变性大细胞淋巴瘤Anaplastic large cell lymphoma,ALK-negative

结外边缘区黏膜相关B细胞淋巴瘤Extranodal marginal-zone B-cell lymphoma

滤泡性淋巴瘤Follicular lymphoma

 

转移性肿瘤METASTATIC TUMOURS

 

男性乳腺肿瘤TUMOURS OF THE MALE BREAST

男性乳腺发育Gynaecomastia

Carcinoma

•浸润癌Invasive carcinoma

•原位癌In situ carcinoma

 

临床类型CLINICAL PATTERNS

炎性乳癌Inflacmatory carcinoma

双乳癌Bliateral breast carcinoma


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